Medetomidine, an α2-agonist, alleviates post-thoracotomy pain in dogs

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Post Thoracotomy Pain Syndrome

Post-thoracotomy pain is one of the most severe and long lasting complications after surgery (1-4) which acutely contributes to limit normal respiratory activity impairing the sputum clearance and reducing ventilatory function (5). Along with limb amputation, thoracotomy is the surgical procedure with the highest risk of severe and long lasting acute postoperative pain (6). Moreover, a chronic ...

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Post Thoracotomy Pain Management

Introduction The pathway of a pain impulse starts with the primary afferent nerve fibers (C and Aδ) whose axons end in the dorsal horn of the spinal cord. Nociceptive information is passed to the contralateral side of the spinal cord and, after synapsing, ascends in the anterolateral system as spinothalamic tracts. The primary areas of the brain that respond to pain stimuli are the somatosensor...

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Pharmacological Management of Post-thoracotomy Pain

Thoracotomy is widely recognised as one of the most painful surgical procedures. The combination of extensive tissue dissection and dynamic respiratory movement postoperatively makes post-thoracotomy pain control particularly challenging. In the short term, inadequate analgesia is associated with respiratory complications, poor mobilisation, delayed discharge and respiratory infections. More im...

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Post-thoracotomy pain syndrome: assessment and intervention.

Surgery is a cornerstone of treatment in early-stage non-small cell lung cancer. Chronic postoperative thoracotomy pain, post-thoracotomy pain syndrome (PTPS), is a condition occurring in 50% of postsurgical patients with lung cancer and is largely unrecognized. This article examines the diagnosis and treatment of PTPS to assist oncology nurses in providing better care to this patient populatio...

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Effects of preemptive epidural analgesia on post-thoracotomy pain.

OBJECTIVE The purpose of this study was to determine whether preemptive thoracic epidural analgesia (TEA) initiated before surgical incision would reduce the severity of acute post-thoracotomy pain and the incidence of chronic post-thoracotomy pain. METHOD Meta-analysis of randomized controlled trials (RCTs). SEARCH STRATEGY MEDLINE, the Cochrane Central Register of Controlled Trials (CENTR...

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ژورنال

عنوان ژورنال: Laboratory Animals

سال: 1994

ISSN: 0023-6772,1758-1117

DOI: 10.1258/002367794780745173